The Fong Laboratory at Harvard Medical School (Department of Medicine, Brigham Regenerative Medicine Center, Brigham and Women’s Hospital) is looking to recruit a postdoctoral fellow interested in understanding gene regulatory mechanisms governing tissue regeneration in zebrafish.
One of the goals is to isolate and characterize the cells that contribute to the regenerating blastema, a heterogeneous population of de-differentiated cells that re-differentiates and gives rise to all cell types comprising the regenerated fin. To this end, we have generated multiple reporter zebrafish lines that enable us to mark and track these early “blastema precursor” cells in the amputated caudal fin stump. We have also used CRISPR/Cas9 technology to knockout candidate genes in zebrafish to probe their roles in fin regeneration. Ultimately, we aim to understand the repertoire of transcription factors and gene regulatory events controlling this highly dynamic process.
Applicants should possess a Ph.D. and/or M.D. degree in Molecular Biology, Cell Biology, Genetics, or a related field. The ideal candidate will have a strong background in fish genetics.
Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to firstname.lastname@example.org.