Fong Lab Publications

PUBLICATIONS

2017

Ho JJ, Cattoglio C, McSwiggen DT, Tjian R and Fong YW. Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells. Genes Dev 2017. Apr 15;31(8):830-844. View in Pubmed

2016

Walker RG, Poggioli T, Katsimpardi L, Buchanan SM, Oh J, Wattrus S, Heidecker B, Fong YW, Rubin LL, Ganz P, Thompson TB, Wagers AJ and Lee RT. Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation. Circ Res 2016; 118(7):1125-42. View in Pubmed

2015

Zhang ET, He Y, Grob P, Fong YW, Nogales E and Tjian R. Architecture of the human XPC DNA repair and stem cell coactivator complex. Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):14817-22. doi: 10.1073/pnas.1520104112. Epub 2015 Nov 16. View in Pubmed

Poggioli T, Vujic A, Yang P, Macias-Trevino C, Uygur AN, Loffredo FS, Pancoast JR, Cho M, Goldstein J, Tandias RM, Gonzalez E, Walker RG, Thompson TB, Wagers AJ, Fong YW and Lee RT. Circulating Growth Differentiation Factor 11/8 levels decline with age. Circ Res 2015; doi:10.1161/CIRCRESAHA. 115.307521. View in Pubmed

Cattoglio C, Zhang ET, Grubisic I, Chiba K, Fong YW and Tjian R. Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2317-26.  View in Pubmed

2014 –

Fong YW, Ho JJ, Inouye C and Tjian R. The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells. eLife 2014 Nov 19;3.  View in Pubmed

Fong YW, Cattoglio C and Tjian R. The intertwined roles of transcription and repair proteins. Mol Cell 2013; 52: 291-302.  View in Pubmed

Fong YW, Cattoglio C, Yamaguchi T and Tjian R. Transcriptional regulation by coactivators in embryonic stem cells. Trends Cell Biol 2012; 6: 292-8.  View in Pubmed

Fong YW, Inouye C, Yamaguchi T, Cattoglio C, Grubisic I and Tjian R. A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells. Cell 2011; 147: 120-31.  View in Pubmed

Fong YW and Zhou Q. Stimulatory effect of splicing factors on transcriptional elongation. Nature 2001; 414: 929-33.  View in Pubmed

Fong YW and Zhou Q. Relief of two built-in autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter. Mol Cell Biol 2000; 16: 5897-907.  View in Pubmed

O’Keeffe B, Fong Y, Chen D, Zhou S and Zhou Q. Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated Tat stimulation of HIV-1 transcription. J Biol Chem 2000; 275: 279-87.  View in Pubmed

Chen D, Fong Y and Zhou Q. Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription. Proc Natl Acad Sci USA 1999; 96: 2728-33.  View in Pubmed